Golgi apparatus membrane protein TVP23 homolog B (TVP23B)
Homo sapiens — UniProt Q9NYZ1
Data last refreshed: (UniProt release unknown)
Key facts
Golgi apparatus membrane protein TVP23 homolog B (TVP23B) is a protein from Homo sapiens identified by UniProt accession Q9NYZ1, 205 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9NYZ1; gene symbol TVP23B.
- Organism: Homo sapiens.
- Length: 205 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, self reported educational attainment and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi apparatus membrane protein TVP23 homolog B |
|---|---|
| UniProt accession | Q9NYZ1 |
| Gene | TVP23B |
| Organism | Homo sapiens |
| Length | 205 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.26
- self reported educational attainment · score 0.11
- inflammatory bowel disease · score 0.07
- Autosomal recessive early-onset inflammatory bowel disease · score 0.06
- inflammatory bowel disease 30 · score 0.06
- ulcerative colitis · score 0.06
- inflammatory bowel disease 1 · score 0.06
- Crohn's disease · score 0.06
- Hirschsprung disease · score 0.06
- lactose intolerance adult type · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYZ1-F1 | alphafold | PREDICTED | 80.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYZ1.
Amino-acid sequence (205 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TVP23B?
The strongest Open Targets associations for TVP23B are neurofibrillary tangles measurement, self reported educational attainment, inflammatory bowel disease, Autosomal recessive early-onset inflammatory bowel disease and inflammatory bowel disease 30.
How long is the TVP23B protein?
The Homo sapiens TVP23B protein (UniProt Q9NYZ1) is 205 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYZ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYZ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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