Mitoferrin-1 (SLC25A37)

About Mitoferrin-1

Mitoferrin-1 (SLC25A37) is a protein from Homo sapiens identified by UniProt accession Q9NYZ2, 338 residues long. MolForge cross-references it against 0 known binders and 149 disease associations.

Target properties

Protein name	Mitoferrin-1
UniProt accession	Q9NYZ2
Gene	SLC25A37
Organism	Homo sapiens
Length	338 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (149)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin · score 0.52
mean corpuscular hemoglobin concentration · score 0.50
neurodegenerative disease · score 0.49
Red cell distribution width · score 0.49
mean corpuscular volume · score 0.48
erythrocyte count · score 0.45
body height · score 0.45
sex hormone-binding globulin measurement · score 0.44
platelet count · score 0.43
body mass index · score 0.42

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NYZ2-F1	alphafold	PREDICTED	77.28	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYZ2.

Amino-acid sequence (338 residues)

MELRSGSVGS QAVARRMDGD SRDGGGGKDA TGSEDYENLP TSASVSTHMT AGAMAGILEH SVMYPVDSVK TRMQSLSPDP KAQYTSIYGA LKKIMRTEGF WRPLRGVNVM IMGAGPAHAM YFACYENMKR TLNDVFHHQG NSHLANGIAG SMATLLHDAV MNPAEVVKQR LQMYNSQHRS AISCIRTVWR TEGLGAFYRS YTTQLTMNIP FQSIHFITYE FLQEQVNPHR TYNPQSHIIS GGLAGALAAA ATTPLDVCKT LLNTQENVAL SLANISGRLS GMANAFRTVY QLNGLAGYFK GIQARVIYQM PSTAISWSVY EFFKYFLTKR QLENRAPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards