Mitoferrin-1 (SLC25A37)
Homo sapiens — UniProt Q9NYZ2
Data last refreshed: (UniProt release unknown)
Key facts
Mitoferrin-1 (SLC25A37) is a protein from Homo sapiens identified by UniProt accession Q9NYZ2, 338 residues long. MolForge cross-references it against 0 known binders and 149 disease associations.
- UniProt accession: Q9NYZ2; gene symbol SLC25A37.
- Organism: Homo sapiens.
- Length: 338 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitoferrin-1 |
|---|---|
| UniProt accession | Q9NYZ2 |
| Gene | SLC25A37 |
| Organism | Homo sapiens |
| Length | 338 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (149)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.52
- mean corpuscular hemoglobin concentration · score 0.50
- neurodegenerative disease · score 0.49
- Red cell distribution width · score 0.49
- mean corpuscular volume · score 0.48
- erythrocyte count · score 0.45
- body height · score 0.45
- sex hormone-binding globulin measurement · score 0.44
- platelet count · score 0.43
- body mass index · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYZ2-F1 | alphafold | PREDICTED | 77.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYZ2.
Amino-acid sequence (338 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC25A37?
The strongest Open Targets associations for SLC25A37 are mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, neurodegenerative disease, Red cell distribution width and mean corpuscular volume.
How long is the SLC25A37 protein?
The Homo sapiens SLC25A37 protein (UniProt Q9NYZ2) is 338 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYZ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYZ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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