G2 and S phase-expressed protein 1 (GTSE1)
Homo sapiens — UniProt Q9NYZ3
Data last refreshed: (UniProt release unknown)
Key facts
G2 and S phase-expressed protein 1 (GTSE1) is a protein from Homo sapiens identified by UniProt accession Q9NYZ3, 739 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q9NYZ3; gene symbol GTSE1.
- Organism: Homo sapiens.
- Length: 739 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, ovarian cancer and low grade glioma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G2 and S phase-expressed protein 1 |
|---|---|
| UniProt accession | Q9NYZ3 |
| Gene | GTSE1 |
| Organism | Homo sapiens |
| Length | 739 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.27
- ovarian cancer · score 0.27
- low grade glioma · score 0.27
- breast adenocarcinoma · score 0.26
- glioblastoma multiforme · score 0.24
- triglyceride measurement · score 0.20
- head and neck squamous cell carcinoma · score 0.19
- squamous cell lung carcinoma · score 0.19
- urinary bladder cancer · score 0.18
- metabolite measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NYZ3-F1 | alphafold | PREDICTED | 50.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NYZ3.
Amino-acid sequence (739 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GTSE1?
The strongest Open Targets associations for GTSE1 are lung adenocarcinoma, ovarian cancer, low grade glioma, breast adenocarcinoma and glioblastoma multiforme.
How long is the GTSE1 protein?
The Homo sapiens GTSE1 protein (UniProt Q9NYZ3) is 739 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NYZ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NYZ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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