Vesicle transport protein USE1 (USE1)
Homo sapiens — UniProt Q9NZ43
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle transport protein USE1 (USE1) is a protein from Homo sapiens identified by UniProt accession Q9NZ43, 259 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q9NZ43; gene symbol USE1.
- Organism: Homo sapiens.
- Length: 259 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte measurement and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle transport protein USE1 |
|---|---|
| UniProt accession | Q9NZ43 |
| Gene | USE1 |
| Organism | Homo sapiens |
| Length | 259 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- reticulocyte measurement · score 0.10
- reticulocyte count · score 0.09
- mean corpuscular volume · score 0.08
- total cholesterol measurement · score 0.06
- sex hormone-binding globulin measurement · score 0.05
- body height · score 0.05
- sleep duration · score 0.04
- triglyceride measurement · score 0.04
- Red cell distribution width · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZ43-F1 | alphafold | PREDICTED | 72.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZ43.
Amino-acid sequence (259 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USE1?
The strongest Open Targets associations for USE1 are neurodegenerative disease, reticulocyte measurement, reticulocyte count, mean corpuscular volume and total cholesterol measurement.
How long is the USE1 protein?
The Homo sapiens USE1 protein (UniProt Q9NZ43) is 259 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZ43 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZ43 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.