Molybdenum cofactor biosynthesis protein 1 (MOCS1)
Homo sapiens — UniProt Q9NZB8
Data last refreshed: (UniProt release unknown)
Key facts
Molybdenum cofactor biosynthesis protein 1 (MOCS1) is a protein from Homo sapiens identified by UniProt accession Q9NZB8, 636 residues long. MolForge cross-references it against 1 known binders and 98 disease associations.
- UniProt accession: Q9NZB8; gene symbol MOCS1.
- Organism: Homo sapiens.
- Length: 636 amino acids.
- Top disease associations (Open Targets): sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, encephalopathy due to sulfite oxidase deficiency and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Molybdenum cofactor biosynthesis protein 1 |
|---|---|
| UniProt accession | Q9NZB8 |
| Gene | MOCS1 |
| Organism | Homo sapiens |
| Length | 636 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- sulfite oxidase deficiency due to molybdenum cofactor deficiency type A · score 0.82
- encephalopathy due to sulfite oxidase deficiency · score 0.57
- body height · score 0.34
- sulfite oxidase deficiency due to molybdenum cofactor deficiency · score 0.34
- intraocular pressure measurement · score 0.32
- platelet count · score 0.31
- neurodegenerative disease · score 0.28
- protein measurement · score 0.24
- genetic disorder · score 0.19
- heel bone mineral density · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZB8-F1 | alphafold | PREDICTED | 79.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZB8.
Amino-acid sequence (636 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOCS1?
The strongest Open Targets associations for MOCS1 are sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, encephalopathy due to sulfite oxidase deficiency, body height, sulfite oxidase deficiency due to molybdenum cofactor deficiency and intraocular pressure measurement.
How long is the MOCS1 protein?
The Homo sapiens MOCS1 protein (UniProt Q9NZB8) is 636 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZB8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZB8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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