Alpha-hemoglobin-stabilizing protein (AHSP)
Homo sapiens — UniProt Q9NZD4
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-hemoglobin-stabilizing protein (AHSP) is a protein from Homo sapiens identified by UniProt accession Q9NZD4, 102 residues long. MolForge cross-references it against 0 known binders and 372 disease associations.
- UniProt accession: Q9NZD4; gene symbol AHSP.
- Organism: Homo sapiens.
- Length: 102 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-hemoglobin-stabilizing protein |
|---|---|
| UniProt accession | Q9NZD4 |
| Gene | AHSP |
| Organism | Homo sapiens |
| Length | 102 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (372)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.43
- mean corpuscular volume · score 0.33
- mean corpuscular hemoglobin concentration · score 0.29
- Red cell distribution width · score 0.21
- diffuse plaque measurement · score 0.13
- Blackfan-Diamond anemia · score 0.11
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.10
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.10
- hemoglobin D disease · score 0.09
- Constitutional sideroblastic anemia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZD4-F1 | alphafold | PREDICTED | 90.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZD4.
Amino-acid sequence (102 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AHSP?
The strongest Open Targets associations for AHSP are mean corpuscular hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, Red cell distribution width and diffuse plaque measurement.
How long is the AHSP protein?
The Homo sapiens AHSP protein (UniProt Q9NZD4) is 102 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZD4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZD4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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