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Ninjurin-2 (NINJ2)

Homo sapiens — UniProt Q9NZG7

Gene: NINJ2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ninjurin-2 (NINJ2) is a protein from Homo sapiens identified by UniProt accession Q9NZG7, 142 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

  • UniProt accession: Q9NZG7; gene symbol NINJ2.
  • Organism: Homo sapiens.
  • Length: 142 amino acids.
  • Top disease associations (Open Targets): platelet count, monocyte count and platelet component distribution width.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameNinjurin-2
UniProt accessionQ9NZG7
GeneNINJ2
OrganismHomo sapiens
Length142 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (85)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.49
  • monocyte count · score 0.47
  • platelet component distribution width · score 0.47
  • lymphocyte count · score 0.45
  • sex hormone-binding globulin measurement · score 0.44
  • mean platelet volume · score 0.43
  • leukocyte count · score 0.41
  • platelet crit · score 0.40
  • stroke · score 0.39
  • monocyte percentage of leukocytes · score 0.39

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NZG7-F1alphafoldPREDICTED66.75—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZG7.

Amino-acid sequence (142 residues)

MESARENIDL QPGSSDPRSQ PINLNHYATK KSVAESMLDV ALFMSNAMRL KAVLEQGPSS HYYTTLVTLI SLSLLLQVVI GVLLVVIARL NLNEVEKQWR LNQLNNAATI LVFFTVVINV FITAFGAHKT GFLAARASRN PL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NINJ2?

The strongest Open Targets associations for NINJ2 are platelet count, monocyte count, platelet component distribution width, lymphocyte count and sex hormone-binding globulin measurement.

How long is the NINJ2 protein?

The Homo sapiens NINJ2 protein (UniProt Q9NZG7) is 142 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NZG7
GeneNINJ2
OrganismHomo sapiens
Length142
Binders0
Diseases85
View on UniProt