Interleukin-36 beta (IL36B)
Homo sapiens — UniProt Q9NZH7
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-36 beta (IL36B) is a protein from Homo sapiens identified by UniProt accession Q9NZH7, 164 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.
- UniProt accession: Q9NZH7; gene symbol IL36B.
- Organism: Homo sapiens.
- Length: 164 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, quality of life during menstruation measurement and drug use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-36 beta |
|---|---|
| UniProt accession | Q9NZH7 |
| Gene | IL36B |
| Organism | Homo sapiens |
| Length | 164 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (117)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.24
- quality of life during menstruation measurement · score 0.21
- drug use measurement · score 0.21
- interleukin 1 receptor antagonist measurement · score 0.17
- neutrophil count · score 0.12
- Myopia · score 0.11
- pathological myopia · score 0.11
- C-reactive protein measurement · score 0.10
- myeloid white cell count · score 0.10
- neoplasm · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZH7-F1 | alphafold | PREDICTED | 55.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZH7.
Amino-acid sequence (164 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL36B?
The strongest Open Targets associations for IL36B are PHF-tau measurement, quality of life during menstruation measurement, drug use measurement, interleukin 1 receptor antagonist measurement and neutrophil count.
How long is the IL36B protein?
The Homo sapiens IL36B protein (UniProt Q9NZH7) is 164 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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