Interleukin-36 gamma (IL36G)
Homo sapiens — UniProt Q9NZH8
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-36 gamma (IL36G) is a protein from Homo sapiens identified by UniProt accession Q9NZH8, 169 residues long. MolForge cross-references it against 0 known binders and 287 disease associations.
- UniProt accession: Q9NZH8; gene symbol IL36G.
- Organism: Homo sapiens.
- Length: 169 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, acute lymphoblastic leukemia and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-36 gamma |
|---|---|
| UniProt accession | Q9NZH8 |
| Gene | IL36G |
| Organism | Homo sapiens |
| Length | 169 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (287)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- acute lymphoblastic leukemia · score 0.13
- neoplasm · score 0.11
- non-small cell lung carcinoma · score 0.10
- psoriasis · score 0.09
- chronic obstructive pulmonary disease · score 0.09
- colitis · score 0.08
- Obesity · score 0.08
- interleukin 1 receptor antagonist measurement · score 0.08
- experimental autoimmune encephalomyelitis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZH8-F1 | alphafold | PREDICTED | 90.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZH8.
Amino-acid sequence (169 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL36G?
The strongest Open Targets associations for IL36G are neurodegenerative disease, acute lymphoblastic leukemia, neoplasm, non-small cell lung carcinoma and psoriasis.
How long is the IL36G protein?
The Homo sapiens IL36G protein (UniProt Q9NZH8) is 169 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZH8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZH8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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