A-type potassium channel modulatory protein KCNIP1 (KCNIP1)
Homo sapiens — UniProt Q9NZI2
Data last refreshed: (UniProt release unknown)
Key facts
A-type potassium channel modulatory protein KCNIP1 (KCNIP1) is a protein from Homo sapiens identified by UniProt accession Q9NZI2, 227 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q9NZI2; gene symbol KCNIP1.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): generalised epilepsy, viral load and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | A-type potassium channel modulatory protein KCNIP1 |
|---|---|
| UniProt accession | Q9NZI2 |
| Gene | KCNIP1 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- generalised epilepsy · score 0.33
- viral load · score 0.31
- protein measurement · score 0.24
- neurofibrillary tangles measurement · score 0.23
- breast adenocarcinoma · score 0.22
- PHF-tau measurement · score 0.20
- FEV/FVC ratio · score 0.15
- gut microbiome measurement · score 0.15
- obesity · score 0.14
- cutaneous melanoma · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZI2-F1 | alphafold | PREDICTED | 78.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZI2.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCNIP1?
The strongest Open Targets associations for KCNIP1 are generalised epilepsy, viral load, protein measurement, neurofibrillary tangles measurement and breast adenocarcinoma.
How long is the KCNIP1 protein?
The Homo sapiens KCNIP1 protein (UniProt Q9NZI2) is 227 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZI2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZI2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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