Transcription factor CP2-like protein 1 (TFCP2L1)
Homo sapiens — UniProt Q9NZI6
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor CP2-like protein 1 (TFCP2L1) is a protein from Homo sapiens identified by UniProt accession Q9NZI6, 479 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q9NZI6; gene symbol TFCP2L1.
- Organism: Homo sapiens.
- Length: 479 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, creatinine measurement and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor CP2-like protein 1 |
|---|---|
| UniProt accession | Q9NZI6 |
| Gene | TFCP2L1 |
| Organism | Homo sapiens |
| Length | 479 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.56
- creatinine measurement · score 0.47
- hemoglobin measurement · score 0.46
- erythrocyte count · score 0.46
- hematocrit · score 0.45
- glomerular filtration rate · score 0.44
- blood urea nitrogen measurement · score 0.44
- urate measurement · score 0.43
- serum urea measurement · score 0.43
- multiple sclerosis · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZI6-F1 | alphafold | PREDICTED | 78.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZI6.
Amino-acid sequence (479 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TFCP2L1?
The strongest Open Targets associations for TFCP2L1 are neurodegenerative disease, creatinine measurement, hemoglobin measurement, erythrocyte count and hematocrit.
How long is the TFCP2L1 protein?
The Homo sapiens TFCP2L1 protein (UniProt Q9NZI6) is 479 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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