Upstream-binding protein 1 (UBP1)
Homo sapiens — UniProt Q9NZI7
Data last refreshed: (UniProt release unknown)
Key facts
Upstream-binding protein 1 (UBP1) is a protein from Homo sapiens identified by UniProt accession Q9NZI7, 540 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q9NZI7; gene symbol UBP1.
- Organism: Homo sapiens.
- Length: 540 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, C-reactive protein measurement and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Upstream-binding protein 1 |
|---|---|
| UniProt accession | Q9NZI7 |
| Gene | UBP1 |
| Organism | Homo sapiens |
| Length | 540 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.29
- C-reactive protein measurement · score 0.29
- serum albumin measurement · score 0.27
- body height · score 0.27
- heel bone mineral density · score 0.25
- neurodegenerative disease · score 0.24
- Alzheimer disease · score 0.24
- lysosomal storage disease · score 0.24
- Parkinson disease · score 0.24
- multiple sclerosis · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZI7-F1 | alphafold | PREDICTED | 74.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZI7.
Amino-acid sequence (540 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBP1?
The strongest Open Targets associations for UBP1 are alkaline phosphatase measurement, C-reactive protein measurement, serum albumin measurement, body height and heel bone mineral density.
How long is the UBP1 protein?
The Homo sapiens UBP1 protein (UniProt Q9NZI7) is 540 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZI7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZI7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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