Denticleless protein homolog (DTL)
Homo sapiens — UniProt Q9NZJ0
Data last refreshed: (UniProt release unknown)
Key facts
Denticleless protein homolog (DTL) is a protein from Homo sapiens identified by UniProt accession Q9NZJ0, 730 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: Q9NZJ0; gene symbol DTL.
- Organism: Homo sapiens.
- Length: 730 amino acids.
- Top disease associations (Open Targets): body height, forced expiratory volume and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Denticleless protein homolog |
|---|---|
| UniProt accession | Q9NZJ0 |
| Gene | DTL |
| Organism | Homo sapiens |
| Length | 730 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- body height · score 0.67
- forced expiratory volume · score 0.44
- neurodegenerative disease · score 0.43
- lean body mass · score 0.40
- appendicular lean mass · score 0.34
- whole body water mass · score 0.31
- anthropometric measurement · score 0.28
- body weights and measures · score 0.28
- base metabolic rate measurement · score 0.28
- birth weight · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZJ0-F1 | alphafold | PREDICTED | 62.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZJ0.
Amino-acid sequence (730 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DTL?
The strongest Open Targets associations for DTL are body height, forced expiratory volume, neurodegenerative disease, lean body mass and appendicular lean mass.
How long is the DTL protein?
The Homo sapiens DTL protein (UniProt Q9NZJ0) is 730 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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