Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3)
Homo sapiens — UniProt Q9NZJ6
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3) is a protein from Homo sapiens identified by UniProt accession Q9NZJ6, 369 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9NZJ6; gene symbol COQ3.
- Organism: Homo sapiens.
- Length: 369 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquinone biosynthesis O-methyltransferase, mitochondrial |
|---|---|
| UniProt accession | Q9NZJ6 |
| Gene | COQ3 |
| Organism | Homo sapiens |
| Length | 369 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- lysosomal storage disease · score 0.28
- serum alanine aminotransferase measurement · score 0.14
- creatinine measurement · score 0.10
- testosterone measurement · score 0.05
- depressive symptom measurement · score 0.03
- metabolite measurement · score 0.03
- mathematical ability · score 0.03
- insomnia measurement · score 0.03
- body height · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZJ6-F1 | alphafold | PREDICTED | 71.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZJ6.
Amino-acid sequence (369 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COQ3?
The strongest Open Targets associations for COQ3 are neurodegenerative disease, lysosomal storage disease, serum alanine aminotransferase measurement, creatinine measurement and testosterone measurement.
How long is the COQ3 protein?
The Homo sapiens COQ3 protein (UniProt Q9NZJ6) is 369 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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