Mitochondrial carrier homolog 1 (MTCH1)
Homo sapiens — UniProt Q9NZJ7
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial carrier homolog 1 (MTCH1) is a protein from Homo sapiens identified by UniProt accession Q9NZJ7, 389 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NZJ7; gene symbol MTCH1.
- Organism: Homo sapiens.
- Length: 389 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neoplasm and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial carrier homolog 1 |
|---|---|
| UniProt accession | Q9NZJ7 |
| Gene | MTCH1 |
| Organism | Homo sapiens |
| Length | 389 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- neoplasm · score 0.04
- hemoglobin measurement · score 0.04
- erythrocyte count · score 0.04
- low density lipoprotein cholesterol measurement · score 0.03
- type 1 diabetes mellitus · score 0.03
- hepatocellular carcinoma · score 0.03
- apolipoprotein B measurement · score 0.03
- total cholesterol measurement · score 0.03
- hematocrit · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZJ7-F1 | alphafold | PREDICTED | 74.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZJ7.
Amino-acid sequence (389 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MTCH1?
The strongest Open Targets associations for MTCH1 are neurodegenerative disease, neoplasm, hemoglobin measurement, erythrocyte count and low density lipoprotein cholesterol measurement.
How long is the MTCH1 protein?
The Homo sapiens MTCH1 protein (UniProt Q9NZJ7) is 389 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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