Zinc finger protein 224 (ZNF224)
Homo sapiens — UniProt Q9NZL3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 224 (ZNF224) is a protein from Homo sapiens identified by UniProt accession Q9NZL3, 707 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9NZL3; gene symbol ZNF224.
- Organism: Homo sapiens.
- Length: 707 amino acids.
- Top disease associations (Open Targets): apolipoprotein B measurement, Familial prostate cancer and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 224 |
|---|---|
| UniProt accession | Q9NZL3 |
| Gene | ZNF224 |
| Organism | Homo sapiens |
| Length | 707 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- apolipoprotein B measurement · score 0.30
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- low density lipoprotein cholesterol measurement · score 0.11
- chronic myelogenous leukemia · score 0.09
- chronic lymphocytic leukemia · score 0.08
- cancer · score 0.03
- melanoma · score 0.02
- acute myeloid leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZL3-F1 | alphafold | PREDICTED | 70.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZL3.
Amino-acid sequence (707 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF224?
The strongest Open Targets associations for ZNF224 are apolipoprotein B measurement, Familial prostate cancer, prostate cancer, prostate carcinoma and low density lipoprotein cholesterol measurement.
How long is the ZNF224 protein?
The Homo sapiens ZNF224 protein (UniProt Q9NZL3) is 707 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZL3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZL3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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