EH domain-containing protein 3 (EHD3)
Homo sapiens — UniProt Q9NZN3
Data last refreshed: (UniProt release unknown)
Key facts
EH domain-containing protein 3 (EHD3) is a protein from Homo sapiens identified by UniProt accession Q9NZN3, 535 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9NZN3; gene symbol EHD3.
- Organism: Homo sapiens.
- Length: 535 amino acids.
- Top disease associations (Open Targets): platelet component distribution width, mean platelet volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EH domain-containing protein 3 |
|---|---|
| UniProt accession | Q9NZN3 |
| Gene | EHD3 |
| Organism | Homo sapiens |
| Length | 535 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- platelet component distribution width · score 0.42
- mean platelet volume · score 0.41
- platelet count · score 0.40
- neutrophil count · score 0.40
- monocyte count · score 0.38
- reticulocyte count · score 0.38
- lymphocyte percentage of leukocytes · score 0.36
- myeloid white cell count · score 0.35
- leukocyte count · score 0.35
- liver fibrosis measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZN3-F1 | alphafold | PREDICTED | 88.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZN3.
Amino-acid sequence (535 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EHD3?
The strongest Open Targets associations for EHD3 are platelet component distribution width, mean platelet volume, platelet count, neutrophil count and monocyte count.
How long is the EHD3 protein?
The Homo sapiens EHD3 protein (UniProt Q9NZN3) is 535 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZN3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZN3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.