Aryl-hydrocarbon-interacting protein-like 1 (AIPL1)
Homo sapiens — UniProt Q9NZN9
Data last refreshed: (UniProt release unknown)
Key facts
Aryl-hydrocarbon-interacting protein-like 1 (AIPL1) is a protein from Homo sapiens identified by UniProt accession Q9NZN9, 384 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.
- UniProt accession: Q9NZN9; gene symbol AIPL1.
- Organism: Homo sapiens.
- Length: 384 amino acids.
- Top disease associations (Open Targets): Leber congenital amaurosis, Cone rod dystrophy and retinitis pigmentosa.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Aryl-hydrocarbon-interacting protein-like 1 |
|---|---|
| UniProt accession | Q9NZN9 |
| Gene | AIPL1 |
| Organism | Homo sapiens |
| Length | 384 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (110)
Diseases linked to this target (Open Targets).
- Leber congenital amaurosis · score 0.78
- Cone rod dystrophy · score 0.64
- retinitis pigmentosa · score 0.52
- cone-rod dystrophy · score 0.49
- Retinal dystrophy · score 0.44
- Abnormality of the eye · score 0.27
- stressful life event measurement · score 0.24
- body fat distribution · score 0.23
- C-reactive protein measurement · score 0.23
- thyroxine measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZN9-F1 | alphafold | PREDICTED | 82.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZN9.
Amino-acid sequence (384 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AIPL1?
The strongest Open Targets associations for AIPL1 are Leber congenital amaurosis, Cone rod dystrophy, retinitis pigmentosa, cone-rod dystrophy and Retinal dystrophy.
How long is the AIPL1 protein?
The Homo sapiens AIPL1 protein (UniProt Q9NZN9) is 384 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZN9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZN9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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