Nuclear pore-associated protein 1 (NPAP1)
Homo sapiens — UniProt Q9NZP6
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore-associated protein 1 (NPAP1) is a protein from Homo sapiens identified by UniProt accession Q9NZP6, 1156 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9NZP6; gene symbol NPAP1.
- Organism: Homo sapiens.
- Length: 1156 amino acids.
- Top disease associations (Open Targets): protein measurement, t-tau:beta-amyloid 1-42 ratio measurement and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore-associated protein 1 |
|---|---|
| UniProt accession | Q9NZP6 |
| Gene | NPAP1 |
| Organism | Homo sapiens |
| Length | 1156 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.30
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.30
- metabolite measurement · score 0.29
- intraocular pressure measurement · score 0.04
- neuroticism measurement · score 0.04
- Prader-Willi syndrome · score 0.02
- acute myeloid leukemia · score 0.01
- Angelman syndrome · score 0.01
- non-small cell lung carcinoma · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZP6-F1 | alphafold | PREDICTED | 36.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZP6.
Amino-acid sequence (1156 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPAP1?
The strongest Open Targets associations for NPAP1 are protein measurement, t-tau:beta-amyloid 1-42 ratio measurement, metabolite measurement, intraocular pressure measurement and neuroticism measurement.
How long is the NPAP1 protein?
The Homo sapiens NPAP1 protein (UniProt Q9NZP6) is 1156 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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