DnaJ homolog subfamily C member 27 (DNAJC27)
Homo sapiens — UniProt Q9NZQ0
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 27 (DNAJC27) is a protein from Homo sapiens identified by UniProt accession Q9NZQ0, 273 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.
- UniProt accession: Q9NZQ0; gene symbol DNAJC27.
- Organism: Homo sapiens.
- Length: 273 amino acids.
- Top disease associations (Open Targets): body fat distribution, systolic blood pressure and waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 27 |
|---|---|
| UniProt accession | Q9NZQ0 |
| Gene | DNAJC27 |
| Organism | Homo sapiens |
| Length | 273 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- body fat distribution · score 0.39
- systolic blood pressure · score 0.37
- waist-hip ratio · score 0.35
- body height · score 0.33
- body weight · score 0.28
- waist circumference · score 0.28
- pulse pressure measurement · score 0.27
- neurodegenerative disease · score 0.27
- eosinophil count · score 0.26
- vital capacity · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZQ0-F1 | alphafold | PREDICTED | 90.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZQ0.
Amino-acid sequence (273 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC27?
The strongest Open Targets associations for DNAJC27 are body fat distribution, systolic blood pressure, waist-hip ratio, body height and body weight.
How long is the DNAJC27 protein?
The Homo sapiens DNAJC27 protein (UniProt Q9NZQ0) is 273 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.