NCK-interacting protein with SH3 domain (NCKIPSD)
Homo sapiens — UniProt Q9NZQ3
Data last refreshed: (UniProt release unknown)
Key facts
NCK-interacting protein with SH3 domain (NCKIPSD) is a protein from Homo sapiens identified by UniProt accession Q9NZQ3, 722 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.
- UniProt accession: Q9NZQ3; gene symbol NCKIPSD.
- Organism: Homo sapiens.
- Length: 722 amino acids.
- Top disease associations (Open Targets): head and neck squamous cell carcinoma, cognitive function measurement and melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NCK-interacting protein with SH3 domain |
|---|---|
| UniProt accession | Q9NZQ3 |
| Gene | NCKIPSD |
| Organism | Homo sapiens |
| Length | 722 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (122)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.21
- cognitive function measurement · score 0.19
- melanoma · score 0.19
- mathematical ability · score 0.19
- gastric adenocarcinoma · score 0.18
- breast carcinoma · score 0.18
- esophageal adenocarcinoma · score 0.18
- colorectal adenocarcinoma · score 0.18
- cutaneous melanoma · score 0.18
- clear cell renal carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZQ3-F1 | alphafold | PREDICTED | 75.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZQ3.
Amino-acid sequence (722 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NCKIPSD?
The strongest Open Targets associations for NCKIPSD are head and neck squamous cell carcinoma, cognitive function measurement, melanoma, mathematical ability and gastric adenocarcinoma.
How long is the NCKIPSD protein?
The Homo sapiens NCKIPSD protein (UniProt Q9NZQ3) is 722 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZQ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZQ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.