Tropomodulin-4 (TMOD4)
Homo sapiens — UniProt Q9NZQ9
Data last refreshed: (UniProt release unknown)
Key facts
Tropomodulin-4 (TMOD4) is a protein from Homo sapiens identified by UniProt accession Q9NZQ9, 345 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q9NZQ9; gene symbol TMOD4.
- Organism: Homo sapiens.
- Length: 345 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, gastric adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tropomodulin-4 |
|---|---|
| UniProt accession | Q9NZQ9 |
| Gene | TMOD4 |
| Organism | Homo sapiens |
| Length | 345 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- gastric adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- endometrial cancer · score 0.13
- urinary bladder cancer · score 0.11
- clear cell renal carcinoma · score 0.11
- chronic kidney disease · score 0.03
- skin cancer · score 0.02
- non-melanoma skin carcinoma · score 0.02
- myocardial infarction · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZQ9-F1 | alphafold | PREDICTED | 86.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZQ9.
Amino-acid sequence (345 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMOD4?
The strongest Open Targets associations for TMOD4 are breast adenocarcinoma, gastric adenocarcinoma, ovarian cancer, endometrial cancer and urinary bladder cancer.
How long is the TMOD4 protein?
The Homo sapiens TMOD4 protein (UniProt Q9NZQ9) is 345 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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