LIM and cysteine-rich domains protein 1 (LMCD1)
Homo sapiens — UniProt Q9NZU5
Data last refreshed: (UniProt release unknown)
Key facts
LIM and cysteine-rich domains protein 1 (LMCD1) is a protein from Homo sapiens identified by UniProt accession Q9NZU5, 365 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.
- UniProt accession: Q9NZU5; gene symbol LMCD1.
- Organism: Homo sapiens.
- Length: 365 amino acids.
- Top disease associations (Open Targets): platelet count, diabetes mellitus and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LIM and cysteine-rich domains protein 1 |
|---|---|
| UniProt accession | Q9NZU5 |
| Gene | LMCD1 |
| Organism | Homo sapiens |
| Length | 365 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (101)
Diseases linked to this target (Open Targets).
- platelet count · score 0.46
- diabetes mellitus · score 0.45
- FEV/FVC ratio · score 0.42
- vital capacity · score 0.36
- platelet crit · score 0.35
- diet measurement · score 0.30
- Mitral valve prolapse · score 0.29
- Varicose veins · score 0.29
- appendicular lean mass · score 0.28
- high density lipoprotein cholesterol measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZU5-F1 | alphafold | PREDICTED | 84.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZU5.
Amino-acid sequence (365 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMCD1?
The strongest Open Targets associations for LMCD1 are platelet count, diabetes mellitus, FEV/FVC ratio, vital capacity and platelet crit.
How long is the LMCD1 protein?
The Homo sapiens LMCD1 protein (UniProt Q9NZU5) is 365 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZU5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZU5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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