Cysteine-rich motor neuron 1 protein (CRIM1)
Homo sapiens — UniProt Q9NZV1
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine-rich motor neuron 1 protein (CRIM1) is a protein from Homo sapiens identified by UniProt accession Q9NZV1, 1036 residues long. MolForge cross-references it against 0 known binders and 310 disease associations.
- UniProt accession: Q9NZV1; gene symbol CRIM1.
- Organism: Homo sapiens.
- Length: 1036 amino acids.
- Top disease associations (Open Targets): body height, chronotype measurement and QRS duration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine-rich motor neuron 1 protein |
|---|---|
| UniProt accession | Q9NZV1 |
| Gene | CRIM1 |
| Organism | Homo sapiens |
| Length | 1036 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (310)
Diseases linked to this target (Open Targets).
- body height · score 0.43
- chronotype measurement · score 0.41
- QRS duration · score 0.41
- FEV/FVC ratio · score 0.41
- vital capacity · score 0.40
- mathematical ability · score 0.36
- electrocardiography · score 0.35
- body mass index · score 0.29
- physical activity measurement · score 0.29
- uric acid measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZV1-F1 | alphafold | PREDICTED | 67.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZV1.
Amino-acid sequence (1036 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CRIM1?
The strongest Open Targets associations for CRIM1 are body height, chronotype measurement, QRS duration, FEV/FVC ratio and vital capacity.
How long is the CRIM1 protein?
The Homo sapiens CRIM1 protein (UniProt Q9NZV1) is 1036 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZV1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZV1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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