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Selenoprotein N (SELENON)

Homo sapiens — UniProt Q9NZV5

Gene: SELENONHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Selenoprotein N (SELENON) is a protein from Homo sapiens identified by UniProt accession Q9NZV5, 590 residues long. MolForge cross-references it against 0 known binders and 416 disease associations.

  • UniProt accession: Q9NZV5; gene symbol SELENON.
  • Organism: Homo sapiens.
  • Length: 590 amino acids.
  • Top disease associations (Open Targets): rigid spine muscular dystrophy 1, Classic multiminicore myopathy and congenital fiber-type disproportion myopathy.

Target properties

Protein nameSelenoprotein N
UniProt accessionQ9NZV5
GeneSELENON
OrganismHomo sapiens
Length590 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (416)

Diseases linked to this target (Open Targets).

  • rigid spine muscular dystrophy 1 · score 0.80
  • Classic multiminicore myopathy · score 0.76
  • congenital fiber-type disproportion myopathy · score 0.65
  • SELENON-related myopathy · score 0.56
  • Joubert syndrome and related disorders · score 0.49
  • cap myopathy · score 0.45
  • childhood-onset nemaline myopathy · score 0.45
  • intermediate nemaline myopathy · score 0.44
  • muscular dystrophy · score 0.43
  • Abnormality of the musculature · score 0.41

3D Structure

Predicted structure for Q9NZV5 is available from the AlphaFold Protein Structure Database.

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZV5.

Amino-acid sequence (590 residues)

MGRARPGQRG PPSPGPAAQP PAPPRRRARS LALLGALLAA AAAAAVRVCA RHAEAQAAAR QELALKTLGT DGLFLFSSLD TDGDMYISPE EFKPIAEKLT GSCSVTQTGV QWCSHSSLQP QLPWLNUSSC LSLLRSTPAA SCEEEELPPD PSEETLTIEA RFQPLLPETM TKSKDGFLGV SRLALSGLRN WTAAASPSAV FATRHFQPFL PPPGQELGEP WWIIPSELSM FTGYLSNNRF YPPPPKGKEV IIHRLLSMFH PRPFVKTRFA PQGAVACLTA ISDFYYTVMF RIHAEFQLSE PPDFPFWFSP AQFTGHIILS KDATHVRDFR LFVPNHRSLN VDMEWLYGAS ESSNMEVDIG YIPQMELEAT GPSVPSVILD EDGSMIDSHL PSGEPLQFVF EEIKWQQELS WEEAARRLEV AMYPFKKVSY LPFTEAFDRA KAENKLVHSI LLWGALDDQS CUGSGRTLRE TVLESSPILT LLNESFISTW SLVKELEELQ NNQENSSHQK LAGLHLEKYS FPVEMMICLP NGTVVHHINA NYFLDITSVK PEEIESNLFS FSSTFEDPST ATYMQFLKEG LRRGLPLLQP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SELENON?

The strongest Open Targets associations for SELENON are rigid spine muscular dystrophy 1, Classic multiminicore myopathy, congenital fiber-type disproportion myopathy, SELENON-related myopathy and Joubert syndrome and related disorders.

How long is the SELENON protein?

The Homo sapiens SELENON protein (UniProt Q9NZV5) is 590 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NZV5
GeneSELENON
OrganismHomo sapiens
Length590
Binders0
Diseases416
View on UniProt