Methionine-R-sulfoxide reductase B1 (MSRB1)
Homo sapiens — UniProt Q9NZV6
Data last refreshed: (UniProt release unknown)
Key facts
Methionine-R-sulfoxide reductase B1 (MSRB1) is a protein from Homo sapiens identified by UniProt accession Q9NZV6, 116 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q9NZV6; gene symbol MSRB1.
- Organism: Homo sapiens.
- Length: 116 amino acids.
- Top disease associations (Open Targets): atrial flutter, atrial fibrillation and hepatocellular carcinoma.
Target properties
| Protein name | Methionine-R-sulfoxide reductase B1 |
|---|---|
| UniProt accession | Q9NZV6 |
| Gene | MSRB1 |
| Organism | Homo sapiens |
| Length | 116 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- atrial flutter · score 0.09
- atrial fibrillation · score 0.09
- hepatocellular carcinoma · score 0.08
- cancer · score 0.08
- neoplasm · score 0.07
- chronic obstructive pulmonary disease · score 0.07
- cardiac arrhythmia · score 0.07
- soluble triggering receptor expressed on myeloid cells 2 measurement · score 0.05
- creatinine measurement · score 0.05
- glomerular filtration rate · score 0.04
3D Structure
Predicted structure for Q9NZV6 is available from the AlphaFold Protein Structure Database.
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZV6.
Amino-acid sequence (116 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MSRB1?
The strongest Open Targets associations for MSRB1 are atrial flutter, atrial fibrillation, hepatocellular carcinoma, cancer and neoplasm.
How long is the MSRB1 protein?
The Homo sapiens MSRB1 protein (UniProt Q9NZV6) is 116 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZV6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZV6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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