Zinc finger imprinted 2 (ZIM2)
Homo sapiens — UniProt Q9NZV7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger imprinted 2 (ZIM2) is a protein from Homo sapiens identified by UniProt accession Q9NZV7, 527 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9NZV7; gene symbol ZIM2.
- Organism: Homo sapiens.
- Length: 527 amino acids.
- Top disease associations (Open Targets): IGF-1 measurement, high density lipoprotein cholesterol measurement and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger imprinted 2 |
|---|---|
| UniProt accession | Q9NZV7 |
| Gene | ZIM2 |
| Organism | Homo sapiens |
| Length | 527 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.16
- high density lipoprotein cholesterol measurement · score 0.15
- triglyceride measurement · score 0.15
- pancreatic adenocarcinoma · score 0.14
- genetic disorder · score 0.12
- colorectal adenocarcinoma · score 0.04
- appendicular lean mass · score 0.03
- Down syndrome · score 0.01
- cancer · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZV7-F1 | alphafold | PREDICTED | 49.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZV7.
Amino-acid sequence (527 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZIM2?
The strongest Open Targets associations for ZIM2 are IGF-1 measurement, high density lipoprotein cholesterol measurement, triglyceride measurement, pancreatic adenocarcinoma and genetic disorder.
How long is the ZIM2 protein?
The Homo sapiens ZIM2 protein (UniProt Q9NZV7) is 527 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZV7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZV7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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