Protein PALS2 (PALS2)
Homo sapiens — UniProt Q9NZW5
Data last refreshed: (UniProt release unknown)
Key facts
Protein PALS2 (PALS2) is a protein from Homo sapiens identified by UniProt accession Q9NZW5, 540 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9NZW5; gene symbol PALS2.
- Organism: Homo sapiens.
- Length: 540 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, self reported educational attainment and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein PALS2 |
|---|---|
| UniProt accession | Q9NZW5 |
| Gene | PALS2 |
| Organism | Homo sapiens |
| Length | 540 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.40
- self reported educational attainment · score 0.40
- mathematical ability · score 0.37
- schizophrenia · score 0.32
- heel bone mineral density · score 0.32
- urate measurement · score 0.32
- cortical surface area measurement · score 0.31
- body mass index · score 0.29
- autism spectrum disorder · score 0.28
- body height · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZW5-F1 | alphafold | PREDICTED | 83.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZW5.
Amino-acid sequence (540 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PALS2?
The strongest Open Targets associations for PALS2 are systolic blood pressure, self reported educational attainment, mathematical ability, schizophrenia and heel bone mineral density.
How long is the PALS2 protein?
The Homo sapiens PALS2 protein (UniProt Q9NZW5) is 540 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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