Charged multivesicular body protein 5 (CHMP5)
Homo sapiens — UniProt Q9NZZ3
Data last refreshed: (UniProt release unknown)
Key facts
Charged multivesicular body protein 5 (CHMP5) is a protein from Homo sapiens identified by UniProt accession Q9NZZ3, 219 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9NZZ3; gene symbol CHMP5.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): HIV infection, glucose measurement and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Charged multivesicular body protein 5 |
|---|---|
| UniProt accession | Q9NZZ3 |
| Gene | CHMP5 |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.46
- glucose measurement · score 0.07
- electrocardiography · score 0.05
- acute lymphoblastic leukemia · score 0.03
- blood phosphate measurement · score 0.03
- microphthalmia with limb anomalies · score 0.03
- axial length measurement · score 0.03
- Abnormal sperm morphology · score 0.02
- bacteriemia · score 0.02
- acute myeloid leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NZZ3-F1 | alphafold | PREDICTED | 79.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NZZ3.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHMP5?
The strongest Open Targets associations for CHMP5 are HIV infection, glucose measurement, electrocardiography, acute lymphoblastic leukemia and blood phosphate measurement.
How long is the CHMP5 protein?
The Homo sapiens CHMP5 protein (UniProt Q9NZZ3) is 219 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NZZ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NZZ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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