Kallikrein-14 (KLK14)
Homo sapiens — UniProt Q9P0G3
Data last refreshed: (UniProt release unknown)
Key facts
Kallikrein-14 (KLK14) is a protein from Homo sapiens identified by UniProt accession Q9P0G3, 251 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q9P0G3; gene symbol KLK14.
- Organism: Homo sapiens.
- Length: 251 amino acids.
- Top disease associations (Open Targets): blood protein measurement, sialic acid-binding Ig-like lectin 9 measurement and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kallikrein-14 |
|---|---|
| UniProt accession | Q9P0G3 |
| Gene | KLK14 |
| Organism | Homo sapiens |
| Length | 251 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.37
- sialic acid-binding Ig-like lectin 9 measurement · score 0.24
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- clear cell renal carcinoma · score 0.18
- esophageal cancer · score 0.17
- gastric adenocarcinoma · score 0.16
- neuroblastoma · score 0.13
- male infertility · score 0.11
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0G3-F1 | alphafold | PREDICTED | 87.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0G3.
Amino-acid sequence (251 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLK14?
The strongest Open Targets associations for KLK14 are blood protein measurement, sialic acid-binding Ig-like lectin 9 measurement, breast adenocarcinoma, prostate adenocarcinoma and clear cell renal carcinoma.
How long is the KLK14 protein?
The Homo sapiens KLK14 protein (UniProt Q9P0G3) is 251 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0G3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0G3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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