NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13)
Homo sapiens — UniProt Q9P0J0
Data last refreshed: (UniProt release unknown)
Key facts
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13) is a protein from Homo sapiens identified by UniProt accession Q9P0J0, 144 residues long. MolForge cross-references it against 0 known binders and 455 disease associations.
- UniProt accession: Q9P0J0; gene symbol NDUFA13.
- Organism: Homo sapiens.
- Length: 144 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, polycystic ovary syndrome and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 |
|---|---|
| UniProt accession | Q9P0J0 |
| Gene | NDUFA13 |
| Organism | Homo sapiens |
| Length | 144 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (455)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.61
- polycystic ovary syndrome · score 0.61
- diabetes mellitus · score 0.60
- type 1 diabetes mellitus · score 0.58
- gestational diabetes · score 0.58
- schizophrenia · score 0.57
- obesity · score 0.57
- prediabetes syndrome · score 0.56
- insulin resistance · score 0.55
- metabolic syndrome · score 0.53
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0J0-F1 | alphafold | PREDICTED | 93.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0J0.
Amino-acid sequence (144 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NDUFA13?
The strongest Open Targets associations for NDUFA13 are type 2 diabetes mellitus, polycystic ovary syndrome, diabetes mellitus, type 1 diabetes mellitus and gestational diabetes.
How long is the NDUFA13 protein?
The Homo sapiens NDUFA13 protein (UniProt Q9P0J0) is 144 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0J0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0J0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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