Large ribosomal subunit protein bL36m (MRPL36)
Homo sapiens — UniProt Q9P0J6
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein bL36m (MRPL36) is a protein from Homo sapiens identified by UniProt accession Q9P0J6, 103 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9P0J6; gene symbol MRPL36.
- Organism: Homo sapiens.
- Length: 103 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein bL36m |
|---|---|
| UniProt accession | Q9P0J6 |
| Gene | MRPL36 |
| Organism | Homo sapiens |
| Length | 103 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- Alzheimer disease · score 0.31
- Parkinson disease · score 0.31
- multiple sclerosis · score 0.31
- lysosomal storage disease · score 0.31
- alcohol drinking · score 0.26
- mitochondrial complex I deficiency · score 0.12
- PHF-tau measurement · score 0.09
- protein measurement · score 0.09
- drug use measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0J6-F1 | alphafold | PREDICTED | 71.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0J6.
Amino-acid sequence (103 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL36?
The strongest Open Targets associations for MRPL36 are neurodegenerative disease, Alzheimer disease, Parkinson disease, multiple sclerosis and lysosomal storage disease.
How long is the MRPL36 protein?
The Homo sapiens MRPL36 protein (UniProt Q9P0J6) is 103 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0J6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0J6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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