Forkhead box protein J2 (FOXJ2)
Homo sapiens — UniProt Q9P0K8
Data last refreshed: (UniProt release unknown)
Key facts
Forkhead box protein J2 (FOXJ2) is a protein from Homo sapiens identified by UniProt accession Q9P0K8, 574 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9P0K8; gene symbol FOXJ2.
- Organism: Homo sapiens.
- Length: 574 amino acids.
- Top disease associations (Open Targets): mean platelet volume, neutrophil count and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Forkhead box protein J2 |
|---|---|
| UniProt accession | Q9P0K8 |
| Gene | FOXJ2 |
| Organism | Homo sapiens |
| Length | 574 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.34
- neutrophil count · score 0.33
- platelet count · score 0.31
- mean corpuscular volume · score 0.26
- mean reticulocyte volume · score 0.23
- neutrophil percentage of leukocytes · score 0.21
- mean corpuscular hemoglobin concentration · score 0.20
- visual perception measurement · score 0.19
- monocyte percentage of leukocytes · score 0.18
- granulocyte percentage of myeloid white cells · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0K8-F1 | alphafold | PREDICTED | 57.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0K8.
Amino-acid sequence (574 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FOXJ2?
The strongest Open Targets associations for FOXJ2 are mean platelet volume, neutrophil count, platelet count, mean corpuscular volume and mean reticulocyte volume.
How long is the FOXJ2 protein?
The Homo sapiens FOXJ2 protein (UniProt Q9P0K8) is 574 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0K8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0K8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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