DOMON domain-containing protein FRRS1L (FRRS1L)
Homo sapiens — UniProt Q9P0K9
Data last refreshed: (UniProt release unknown)
Key facts
DOMON domain-containing protein FRRS1L (FRRS1L) is a protein from Homo sapiens identified by UniProt accession Q9P0K9, 293 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9P0K9; gene symbol FRRS1L.
- Organism: Homo sapiens.
- Length: 293 amino acids.
- Top disease associations (Open Targets): developmental and epileptic encephalopathy, Seizure and Benign familial chorea.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DOMON domain-containing protein FRRS1L |
|---|---|
| UniProt accession | Q9P0K9 |
| Gene | FRRS1L |
| Organism | Homo sapiens |
| Length | 293 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy · score 0.57
- Seizure · score 0.48
- Benign familial chorea · score 0.47
- Progressive encephalopathy · score 0.47
- chorea · score 0.47
- genetic disorder · score 0.41
- body fat percentage · score 0.39
- autosomal recessive non-syndromic intellectual disability · score 0.37
- fat body mass · score 0.31
- Young adult-onset Parkinsonism · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0K9-F1 | alphafold | PREDICTED | 79.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0K9.
Amino-acid sequence (293 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FRRS1L?
The strongest Open Targets associations for FRRS1L are developmental and epileptic encephalopathy, Seizure, Benign familial chorea, Progressive encephalopathy and chorea.
How long is the FRRS1L protein?
The Homo sapiens FRRS1L protein (UniProt Q9P0K9) is 293 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0K9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0K9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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