Vesicle-associated membrane protein-associated protein A (VAPA)
Homo sapiens — UniProt Q9P0L0
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle-associated membrane protein-associated protein A (VAPA) is a protein from Homo sapiens identified by UniProt accession Q9P0L0, 249 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9P0L0; gene symbol VAPA.
- Organism: Homo sapiens.
- Length: 249 amino acids.
- Top disease associations (Open Targets): hair shape measurement, balding measurement and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle-associated membrane protein-associated protein A |
|---|---|
| UniProt accession | Q9P0L0 |
| Gene | VAPA |
| Organism | Homo sapiens |
| Length | 249 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.25
- balding measurement · score 0.25
- FEV/FVC ratio · score 0.24
- heel bone mineral density · score 0.22
- peak expiratory flow · score 0.22
- forced expiratory volume · score 0.17
- phenylalanine measurement · score 0.13
- basophil count · score 0.10
- alopecia · score 0.09
- bone quantitative ultrasound measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0L0-F1 | alphafold | PREDICTED | 78.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0L0.
Amino-acid sequence (249 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VAPA?
The strongest Open Targets associations for VAPA are hair shape measurement, balding measurement, FEV/FVC ratio, heel bone mineral density and peak expiratory flow.
How long is the VAPA protein?
The Homo sapiens VAPA protein (UniProt Q9P0L0) is 249 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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