Zinc finger protein with KRAB and SCAN domains 7 (ZKSCAN7)
Homo sapiens — UniProt Q9P0L1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein with KRAB and SCAN domains 7 (ZKSCAN7) is a protein from Homo sapiens identified by UniProt accession Q9P0L1, 754 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q9P0L1; gene symbol ZKSCAN7.
- Organism: Homo sapiens.
- Length: 754 amino acids.
- Top disease associations (Open Targets): urate measurement, particulate matter air pollution measurement and major depressive disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein with KRAB and SCAN domains 7 |
|---|---|
| UniProt accession | Q9P0L1 |
| Gene | ZKSCAN7 |
| Organism | Homo sapiens |
| Length | 754 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.14
- particulate matter air pollution measurement · score 0.08
- major depressive disorder · score 0.07
- unipolar depression · score 0.07
- IGF-1 measurement · score 0.06
- depressive symptom measurement · score 0.05
- C-reactive protein measurement · score 0.05
- cystatin C measurement · score 0.04
- immunodeficiency 75 · score 0.04
- autoinflammation with episodic fever and lymphadenopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0L1-F1 | alphafold | PREDICTED | 65.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0L1.
Amino-acid sequence (754 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZKSCAN7?
The strongest Open Targets associations for ZKSCAN7 are urate measurement, particulate matter air pollution measurement, major depressive disorder, unipolar depression and IGF-1 measurement.
How long is the ZKSCAN7 protein?
The Homo sapiens ZKSCAN7 protein (UniProt Q9P0L1) is 754 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0L1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0L1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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