Polycystin-2-like protein 1 (PKD2L1)
Homo sapiens — UniProt Q9P0L9
Data last refreshed: (UniProt release unknown)
Key facts
Polycystin-2-like protein 1 (PKD2L1) is a protein from Homo sapiens identified by UniProt accession Q9P0L9, 805 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9P0L9; gene symbol PKD2L1.
- Organism: Homo sapiens.
- Length: 805 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, mean platelet volume and blood metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polycystin-2-like protein 1 |
|---|---|
| UniProt accession | Q9P0L9 |
| Gene | PKD2L1 |
| Organism | Homo sapiens |
| Length | 805 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.40
- mean platelet volume · score 0.39
- blood metabolite measurement · score 0.39
- heel bone mineral density · score 0.39
- Red cell distribution width · score 0.38
- lymphocyte count · score 0.38
- alkaline phosphatase measurement · score 0.37
- fatty acid measurement · score 0.36
- low density lipoprotein cholesterol measurement · score 0.35
- monocyte count · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0L9-F1 | alphafold | PREDICTED | 75.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0L9.
Amino-acid sequence (805 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PKD2L1?
The strongest Open Targets associations for PKD2L1 are serum metabolite measurement, mean platelet volume, blood metabolite measurement, heel bone mineral density and Red cell distribution width.
How long is the PKD2L1 protein?
The Homo sapiens PKD2L1 protein (UniProt Q9P0L9) is 805 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0L9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0L9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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