GSK3B-interacting protein (GSKIP)
Homo sapiens — UniProt Q9P0R6
Data last refreshed: (UniProt release unknown)
Key facts
GSK3B-interacting protein (GSKIP) is a protein from Homo sapiens identified by UniProt accession Q9P0R6, 139 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9P0R6; gene symbol GSKIP.
- Organism: Homo sapiens.
- Length: 139 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, urate measurement and C-reactive protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GSK3B-interacting protein |
|---|---|
| UniProt accession | Q9P0R6 |
| Gene | GSKIP |
| Organism | Homo sapiens |
| Length | 139 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.07
- urate measurement · score 0.04
- C-reactive protein measurement · score 0.04
- Neonatal acute respiratory distress with surfactant metabolism deficiency · score 0.04
- surfactant metabolism dysfunction, pulmonary, 1 · score 0.03
- non-small cell lung carcinoma · score 0.02
- electrocardiography · score 0.02
- creatinine measurement · score 0.02
- neuroblastoma · score 0.01
- myeloid neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0R6-F1 | alphafold | PREDICTED | 83.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0R6.
Amino-acid sequence (139 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GSKIP?
The strongest Open Targets associations for GSKIP are neurodegenerative disease, urate measurement, C-reactive protein measurement, Neonatal acute respiratory distress with surfactant metabolism deficiency and surfactant metabolism dysfunction, pulmonary, 1.
How long is the GSKIP protein?
The Homo sapiens GSKIP protein (UniProt Q9P0R6) is 139 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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