ORM1-like protein 1 (ORMDL1)
Homo sapiens — UniProt Q9P0S3
Data last refreshed: (UniProt release unknown)
Key facts
ORM1-like protein 1 (ORMDL1) is a protein from Homo sapiens identified by UniProt accession Q9P0S3, 153 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9P0S3; gene symbol ORMDL1.
- Organism: Homo sapiens.
- Length: 153 amino acids.
- Top disease associations (Open Targets): ferritin measurement, diffuse large B-cell lymphoma and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ORM1-like protein 1 |
|---|---|
| UniProt accession | Q9P0S3 |
| Gene | ORMDL1 |
| Organism | Homo sapiens |
| Length | 153 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- ferritin measurement · score 0.19
- diffuse large B-cell lymphoma · score 0.07
- Red cell distribution width · score 0.07
- neoplasm · score 0.06
- cancer · score 0.05
- liver iron measurement · score 0.02
- ovarian carcinoma · score 0.01
- ulcerative colitis · score 0.01
- Lynch syndrome · score 0.01
- Thymoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0S3-F1 | alphafold | PREDICTED | 93.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0S3.
Amino-acid sequence (153 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ORMDL1?
The strongest Open Targets associations for ORMDL1 are ferritin measurement, diffuse large B-cell lymphoma, Red cell distribution width, neoplasm and cancer.
How long is the ORMDL1 protein?
The Homo sapiens ORMDL1 protein (UniProt Q9P0S3) is 153 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0S3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0S3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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