Zinc finger protein 581 (ZNF581)
Homo sapiens — UniProt Q9P0T4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 581 (ZNF581) is a protein from Homo sapiens identified by UniProt accession Q9P0T4, 197 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9P0T4; gene symbol ZNF581.
- Organism: Homo sapiens.
- Length: 197 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, triple-negative breast cancer and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 581 |
|---|---|
| UniProt accession | Q9P0T4 |
| Gene | ZNF581 |
| Organism | Homo sapiens |
| Length | 197 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- triple-negative breast cancer · score 0.03
- high density lipoprotein cholesterol measurement · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- neoplasm · score 0.01
- viral disease · score 0.00
- Obesity · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0T4-F1 | alphafold | PREDICTED | 68.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0T4.
Amino-acid sequence (197 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF581?
The strongest Open Targets associations for ZNF581 are neurodegenerative disease, triple-negative breast cancer, high density lipoprotein cholesterol measurement, systemic juvenile idiopathic arthritis and neoplasm.
How long is the ZNF581 protein?
The Homo sapiens ZNF581 protein (UniProt Q9P0T4) is 197 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0T4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0T4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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