CXXC-type zinc finger protein 1 (CXXC1)
Homo sapiens — UniProt Q9P0U4
Data last refreshed: (UniProt release unknown)
Key facts
CXXC-type zinc finger protein 1 (CXXC1) is a protein from Homo sapiens identified by UniProt accession Q9P0U4, 656 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9P0U4; gene symbol CXXC1.
- Organism: Homo sapiens.
- Length: 656 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, multiple sclerosis and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CXXC-type zinc finger protein 1 |
|---|---|
| UniProt accession | Q9P0U4 |
| Gene | CXXC1 |
| Organism | Homo sapiens |
| Length | 656 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- multiple sclerosis · score 0.37
- Parkinson disease · score 0.37
- lysosomal storage disease · score 0.37
- Alzheimer disease · score 0.37
- body height · score 0.23
- whole body water mass · score 0.21
- appendicular lean mass · score 0.17
- cancer · score 0.07
- lung adenocarcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0U4-F1 | alphafold | PREDICTED | 69.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0U4.
Amino-acid sequence (656 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CXXC1?
The strongest Open Targets associations for CXXC1 are neurodegenerative disease, multiple sclerosis, Parkinson disease, lysosomal storage disease and Alzheimer disease.
How long is the CXXC1 protein?
The Homo sapiens CXXC1 protein (UniProt Q9P0U4) is 656 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0U4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0U4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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