SH3 domain-binding protein 4 (SH3BP4)
Homo sapiens — UniProt Q9P0V3
Data last refreshed: (UniProt release unknown)
Key facts
SH3 domain-binding protein 4 (SH3BP4) is a protein from Homo sapiens identified by UniProt accession Q9P0V3, 963 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9P0V3; gene symbol SH3BP4.
- Organism: Homo sapiens.
- Length: 963 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, platelet count and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SH3 domain-binding protein 4 |
|---|---|
| UniProt accession | Q9P0V3 |
| Gene | SH3BP4 |
| Organism | Homo sapiens |
| Length | 963 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- platelet count · score 0.45
- platelet crit · score 0.38
- cholelithiasis · score 0.29
- protein measurement · score 0.29
- systolic blood pressure · score 0.29
- diastolic blood pressure · score 0.26
- asthma · score 0.19
- allergic disease · score 0.19
- self reported educational attainment · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0V3-F1 | alphafold | PREDICTED | 69.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0V3.
Amino-acid sequence (963 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SH3BP4?
The strongest Open Targets associations for SH3BP4 are neurodegenerative disease, platelet count, platelet crit, cholelithiasis and protein measurement.
How long is the SH3BP4 protein?
The Homo sapiens SH3BP4 protein (UniProt Q9P0V3) is 963 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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