SLAM family member 8 (SLAMF8)
Homo sapiens — UniProt Q9P0V8
Data last refreshed: (UniProt release unknown)
Key facts
SLAM family member 8 (SLAMF8) is a protein from Homo sapiens identified by UniProt accession Q9P0V8, 285 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q9P0V8; gene symbol SLAMF8.
- Organism: Homo sapiens.
- Length: 285 amino acids.
- Top disease associations (Open Targets): Crohn's disease, inflammatory bowel disease and anaplastic large cell lymphoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLAM family member 8 |
|---|---|
| UniProt accession | Q9P0V8 |
| Gene | SLAMF8 |
| Organism | Homo sapiens |
| Length | 285 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- Crohn's disease · score 0.26
- inflammatory bowel disease · score 0.15
- anaplastic large cell lymphoma · score 0.07
- Immunodeficiency due to a late component of complements deficiency · score 0.07
- immunodeficiency 35 · score 0.06
- neoplasm · score 0.06
- isolated agammaglobulinemia · score 0.06
- recurrent Neisseria infections due to factor D deficiency · score 0.05
- pulmonary tuberculosis · score 0.05
- hyper-IgM syndrome type 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0V8-F1 | alphafold | PREDICTED | 81.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0V8.
Amino-acid sequence (285 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLAMF8?
The strongest Open Targets associations for SLAMF8 are Crohn's disease, inflammatory bowel disease, anaplastic large cell lymphoma, Immunodeficiency due to a late component of complements deficiency and immunodeficiency 35.
How long is the SLAMF8 protein?
The Homo sapiens SLAMF8 protein (UniProt Q9P0V8) is 285 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0V8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0V8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.