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Septin-10 (SEPTIN10)

Homo sapiens — UniProt Q9P0V9

Gene: SEPTIN10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Septin-10 (SEPTIN10) is a protein from Homo sapiens identified by UniProt accession Q9P0V9, 454 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

  • UniProt accession: Q9P0V9; gene symbol SEPTIN10.
  • Organism: Homo sapiens.
  • Length: 454 amino acids.
  • Top disease associations (Open Targets): platelet count, platelet crit and bone density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSeptin-10
UniProt accessionQ9P0V9
GeneSEPTIN10
OrganismHomo sapiens
Length454 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (89)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.42
  • platelet crit · score 0.33
  • bone density · score 0.32
  • urate measurement · score 0.32
  • schizophrenia · score 0.32
  • body fat percentage · score 0.08
  • azoospermia · score 0.07
  • physical activity · score 0.06
  • male infertility with teratozoospermia due to single gene mutation · score 0.05
  • partial chromosome Y deletion · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9P0V9-F1alphafoldPREDICTED80.71—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0V9.

Amino-acid sequence (454 residues)

MASSEVARHL LFQSHMATKT TCMSSQGSDD EQIKRENIRS LTMSGHVGFE SLPDQLVNRS IQQGFCFNIL CVGETGIGKS TLIDTLFNTN FEDYESSHFC PNVKLKAQTY ELQESNVQLK LTIVNTVGFG DQINKEESYQ PIVDYIDAQF EAYLQEELKI KRSLFTYHDS RIHVCLYFIS PTGHSLKTLD LLTMKNLDSK VNIIPVIAKA DTVSKTELQK FKIKLMSELV SNGVQIYQFP TDDDTIAKVN AAMNGQLPFA VVGSMDEVKV GNKMVKARQY PWGVVQVENE NHCDFVKLRE MLICTNMEDL REQTHTRHYE LYRRCKLEEM GFTDVGPENK PVSVQETYEA KRHEFHGERQ RKEEEMKQMF VQRVKEKEAI LKEAERELQA KFEHLKRLHQ EERMKLEEKR RLLEEEIIAF SKKKATSEIF HSQSFLATGS NLRKDKDRKN SNFL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SEPTIN10?

The strongest Open Targets associations for SEPTIN10 are platelet count, platelet crit, bone density, urate measurement and schizophrenia.

How long is the SEPTIN10 protein?

The Homo sapiens SEPTIN10 protein (UniProt Q9P0V9) is 454 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9P0V9
GeneSEPTIN10
OrganismHomo sapiens
Length454
Binders0
Diseases89
View on UniProt