Interferon kappa (IFNK)
Homo sapiens — UniProt Q9P0W0
Data last refreshed: (UniProt release unknown)
Key facts
Interferon kappa (IFNK) is a protein from Homo sapiens identified by UniProt accession Q9P0W0, 207 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q9P0W0; gene symbol IFNK.
- Organism: Homo sapiens.
- Length: 207 amino acids.
- Top disease associations (Open Targets): amyotrophic lateral sclerosis, sporadic amyotrophic lateral sclerosis and hair colour measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interferon kappa |
|---|---|
| UniProt accession | Q9P0W0 |
| Gene | IFNK |
| Organism | Homo sapiens |
| Length | 207 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- amyotrophic lateral sclerosis · score 0.24
- sporadic amyotrophic lateral sclerosis · score 0.15
- hair colour measurement · score 0.14
- body mass index · score 0.13
- Brain atrophy · score 0.12
- lean body mass · score 0.12
- blood protein measurement · score 0.11
- mean platelet volume · score 0.11
- motor neuron disease · score 0.11
- body weight · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0W0-F1 | alphafold | PREDICTED | 82.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0W0.
Amino-acid sequence (207 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IFNK?
The strongest Open Targets associations for IFNK are amyotrophic lateral sclerosis, sporadic amyotrophic lateral sclerosis, hair colour measurement, body mass index and Brain atrophy.
How long is the IFNK protein?
The Homo sapiens IFNK protein (UniProt Q9P0W0) is 207 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0W0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0W0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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