Peroxisomal sarcosine oxidase (PIPOX)
Homo sapiens — UniProt Q9P0Z9
Data last refreshed: (UniProt release unknown)
Key facts
Peroxisomal sarcosine oxidase (PIPOX) is a protein from Homo sapiens identified by UniProt accession Q9P0Z9, 390 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q9P0Z9; gene symbol PIPOX.
- Organism: Homo sapiens.
- Length: 390 amino acids.
- Top disease associations (Open Targets): unipolar depression, monocyte count and bipolar disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peroxisomal sarcosine oxidase |
|---|---|
| UniProt accession | Q9P0Z9 |
| Gene | PIPOX |
| Organism | Homo sapiens |
| Length | 390 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- unipolar depression · score 0.22
- monocyte count · score 0.20
- bipolar disorder · score 0.16
- BMI-adjusted hip circumference · score 0.16
- grip strength measurement · score 0.14
- smoking status measurement · score 0.14
- Low-frequency sensorineural hearing impairment · score 0.12
- smoking initiation · score 0.10
- cigarettes per day measurement · score 0.10
- functional brain measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P0Z9-F1 | alphafold | PREDICTED | 94.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P0Z9.
Amino-acid sequence (390 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PIPOX?
The strongest Open Targets associations for PIPOX are unipolar depression, monocyte count, bipolar disorder, BMI-adjusted hip circumference and grip strength measurement.
How long is the PIPOX protein?
The Homo sapiens PIPOX protein (UniProt Q9P0Z9) is 390 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P0Z9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P0Z9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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