Disks large-associated protein 2 (DLGAP2)
Homo sapiens — UniProt Q9P1A6
Data last refreshed: (UniProt release unknown)
Key facts
Disks large-associated protein 2 (DLGAP2) is a protein from Homo sapiens identified by UniProt accession Q9P1A6, 1054 residues long. MolForge cross-references it against 0 known binders and 109 disease associations.
- UniProt accession: Q9P1A6; gene symbol DLGAP2.
- Organism: Homo sapiens.
- Length: 1054 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, urate measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Disks large-associated protein 2 |
|---|---|
| UniProt accession | Q9P1A6 |
| Gene | DLGAP2 |
| Organism | Homo sapiens |
| Length | 1054 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (109)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.34
- urate measurement · score 0.30
- bone density · score 0.30
- platelet component distribution width · score 0.29
- functional gastric disease · score 0.24
- PHF-tau measurement · score 0.24
- metabolite measurement · score 0.23
- thyroid gland adenocarcinoma · score 0.18
- daytime rest measurement · score 0.17
- wellbeing measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1A6-F1 | alphafold | PREDICTED | 48.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1A6.
Amino-acid sequence (1054 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DLGAP2?
The strongest Open Targets associations for DLGAP2 are self reported educational attainment, urate measurement, bone density, platelet component distribution width and functional gastric disease.
How long is the DLGAP2 protein?
The Homo sapiens DLGAP2 protein (UniProt Q9P1A6) is 1054 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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