Trace amine-associated receptor 2 (TAAR2)
Homo sapiens — UniProt Q9P1P5
Data last refreshed: (UniProt release unknown)
Key facts
Trace amine-associated receptor 2 (TAAR2) is a protein from Homo sapiens identified by UniProt accession Q9P1P5, 351 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q9P1P5; gene symbol TAAR2.
- Organism: Homo sapiens.
- Length: 351 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, cutaneous melanoma and esophageal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trace amine-associated receptor 2 |
|---|---|
| UniProt accession | Q9P1P5 |
| Gene | TAAR2 |
| Organism | Homo sapiens |
| Length | 351 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- cutaneous melanoma · score 0.17
- esophageal cancer · score 0.13
- squamous cell lung carcinoma · score 0.12
- neuroblastoma · score 0.11
- breast adenocarcinoma · score 0.10
- Parkinson disease · score 0.00
- Hyperglycemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1P5-F1 | alphafold | PREDICTED | 88.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1P5.
Amino-acid sequence (351 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAAR2?
The strongest Open Targets associations for TAAR2 are lung adenocarcinoma, cutaneous melanoma, esophageal cancer, squamous cell lung carcinoma and neuroblastoma.
How long is the TAAR2 protein?
The Homo sapiens TAAR2 protein (UniProt Q9P1P5) is 351 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1P5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1P5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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