Olfactory receptor 1A1 (OR1A1)
Homo sapiens — UniProt Q9P1Q5
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 1A1 (OR1A1) is a protein from Homo sapiens identified by UniProt accession Q9P1Q5, 309 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9P1Q5; gene symbol OR1A1.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): neuroblastoma, clear cell renal carcinoma and low grade glioma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 1A1 |
|---|---|
| UniProt accession | Q9P1Q5 |
| Gene | OR1A1 |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- low grade glioma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- gastric carcinoma · score 0.01
- Anosmia · score 0.00
- neoplasm · score 0.00
- nail-patella syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1Q5-F1 | alphafold | PREDICTED | 89.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1Q5.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR1A1?
The strongest Open Targets associations for OR1A1 are neuroblastoma, clear cell renal carcinoma, low grade glioma, pancreatic adenocarcinoma and ovarian cancer.
How long is the OR1A1 protein?
The Homo sapiens OR1A1 protein (UniProt Q9P1Q5) is 309 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1Q5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1Q5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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