MyoD family inhibitor domain-containing protein…

About MyoD family inhibitor domain-containing protein

MyoD family inhibitor domain-containing protein (MDFIC) is a protein from Homo sapiens identified by UniProt accession Q9P1T7, 246 residues long. MolForge cross-references it against 0 known binders and 108 disease associations.

Target properties

Protein name	MyoD family inhibitor domain-containing protein
UniProt accession	Q9P1T7
Gene	MDFIC
Organism	Homo sapiens
Length	246 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (108)

Diseases linked to this target (Open Targets).

lymphatic malformation 12 · score 0.57
monocyte count · score 0.43
neuroticism measurement · score 0.41
self reported educational attainment · score 0.41
mathematical ability · score 0.39
mitochondrial DNA measurement · score 0.37
cytotoxicity measurement · score 0.32
response to clozapine · score 0.32
risk-taking behaviour · score 0.30
body weight · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P1T7-F1	alphafold	PREDICTED	52.90	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1T7.

Amino-acid sequence (246 residues)

MSGAGEALAP GPVGPQRVAE AGGGQLGSTA QGKCDKDNTE KDITQATNSH FTHGEMQDQS IWGNPSDGEL IRTQPQRLPQ LQTSAQVPSG EEIGKIKNGH TGLSNGNGIH HGAKHGSADN RKLSAPVSQK MHRKIQSSLS VNSDISKKSK VNAVFSQKTG SSPEDCCVHC ILACLFCEFL TLCNIVLGQA SCGICTSEAC CCCCGDEMGD DCNCPCDMDC GIMDACCESS DCLEICMECC GICFPS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

MyoD family inhibitor domain-containing protein (MDFIC)